Usage

Lysozyme is a naturally occurring enzyme found in various bodily secretions such as tears, saliva, and milk. It has antimicrobial properties and plays a role in the body's defense against bacterial infections.

Lysozyme has various applications in different fields. It is used in the food industry as a natural preservative due to its antimicrobial properties. It is also used in medical and pharmaceutical applications, such as in the treatment of gastrointestinal disorders in infants and as a component in some antiviral medications

Dosage

The dosage of lysozyme can vary depending on the specific formulation, indication, and individual factors. It is important to follow the dosage instructions provided by your healthcare professional or the product labeling. Here is some information on the dosage of lysozyme based on the search results:

• Lysozyme chloride: Lysozyme chloride is available in tablet form with a dosage strength of 90mg. The specific dosage instructions for lysozyme chloride may vary depending on the condition being treated. It is recommended to consult with a healthcare professional for the appropriate dosage and duration of treatment.

• Leftose: Leftose is a product containing lysozyme in tablet form with a dosage strength of 30mg. It is a natural and non-drowsy product used for various purposes. The specific dosage instructions for Leftose may vary depending on the condition being treated. It is advisable to follow the instructions provided by the manufacturer or consult with a healthcare professional.

Side Effects

Lysozyme is an enzyme that is used for various purposes, including the treatment of certain medical conditions. Here is some information on the side effects of lysozyme:

• Possible side effects: Some possible side effects of lysozyme may include rash, redness, anorexia (loss of appetite), gastrointestinal upset, hypersensitivity reactions, drowsiness, dizziness, hypotension (low blood pressure), headache, and gastrointestinal disturbances. It is important to note that these side effects may not occur in everyone and can vary depending on the individual and the specific formulation of lysozyme being used.

• Controversy and efficacy: There is some controversy surrounding the efficacy of lysozyme-containing products, with varying opinions on their benefits and effectiveness. It is advisable to consult with a healthcare professional for more specific information regarding the efficacy and potential side effects of lysozyme in the context of your specific condition.

Precaution

When using lysozyme, there are a few precautions to keep in mind:

1. Allergies: If you are allergic to lysozyme or any of its ingredients, it is important to avoid using it. Allergic reactions can range from mild symptoms like rash and redness to more severe reactions. If you experience any signs of an allergic reaction, such as difficulty breathing or swelling of the face, seek immediate medical attention.

2. Ruminant animals: Ruminant animals, such as cows and yaks, have been considered lysozyme deficient in certain bodily fluids like tears, milk, and blood. However, in their stomachs, lysozymes are recruited as digestive enzymes to exploit plant material as a food resource. This information is relevant for understanding the natural occurrence of lysozyme in different species.

3. Efficacy controversy: There is controversy surrounding the efficacy of lysozyme-containing products, with some people claiming it as a wonder drug while others dismiss it as a placebo. The Health Sciences Authority (HSA) in Singapore has conducted a re-evaluation of the benefit-risk profile of lysozyme and concluded that it has failed to show efficacy. As a result, the use of lysozyme in therapeutic products will be phased out in Singapore.

Overdose

In case of an overdose of lysozyme, it is important to talk to your doctor to control the possible risks. However, specific information about the effects of lysozyme overdose is limited. If you accidentally miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule to avoid doubling the dose.

​

It is worth noting that the Health Sciences Authority (HSA) in Singapore has conducted a re-evaluation of the benefit-risk profile of lysozyme and concluded that it has failed to show efficacy. As a result, the use of lysozyme in therapeutic products will be phased out in Singapore.

Interaction

The interactions of lysozyme can vary depending on the context. Here are a few examples of lysozyme interactions:

1. Gastrointestinal disorders: Lysozyme is indicated for the treatment of gastrointestinal disorders in infants.

2. Herpes zoster and Herpes simplex: Lysozyme is also used in the treatment of Herpes zoster and Herpes simplex.

3. Protein interactions: Lysozyme can interact with other proteins and molecules. For example, studies have been conducted on the interaction of lysozyme with negatively charged lipid bilayers, which can lead to conformational variations and aggregation of the protein. Additionally, the interaction of lysozyme with drugs has been studied to understand the structural features of proteins and the therapeutic effectiveness of drugs.

4. Formation of composites: Lysozyme can interact with silica, leading to the formation of composites with different characteristics from pure silica.

Mechanism

The mechanism of lysozyme involves its ability to break down bacterial cell walls, leading to the lysis of bacterial cells. This mechanism is thought to contribute to the reduction of infection severity and promotion of healing in the human body. Lysozyme has direct antibacterial activity and also exhibits immunomodulatory and anti-inflammatory effects. It stimulates the production of white blood cells, which are responsible for fighting infections.

The catalytic activity of lysozyme is influenced by factors such as pH and temperature. The enzyme's optimum pH and temperature may vary depending on the source of isolation and purification. The hydrolysis mechanism of lysozyme has been studied, and high-resolution X-ray structural analysis has provided insights into the hydrogen-bond network and catalytic residues involved.

It is important to note that lysozyme is used as a therapeutic agent in the treatment of gastrointestinal disorders in infants and certain viral infections like Herpes zoster and Herpes simplex. However, the specific mechanisms of action for these indications may involve additional factors beyond the direct antibacterial activity of lysozyme.

Disclaimer

It is important to talk to a healthcare provider or pharmacist about all medications and supplements being taken, to determine whether any interactions may occur. They can advise on the appropriate use and dosage of aspirin to avoid any potential drug interactions.